張研（中國青年女科學(xué)家）
人物簡介
張研，女，北京大學(xué)生命科學(xué)學(xué)院神經(jīng)科學(xué)教授。
教育經(jīng)歷
1999 - 2003 , 理學(xué)博士 , Neurology and Neurosurgery , McGill University1997 - 1999 , 理學(xué)碩士 , Neuroscience , Carleton University1993 - 1997 , 理學(xué)學(xué)士 , Psychology , Peking University
科研領(lǐng)域
1. Cell death in neurodegenerative diseases神經(jīng)退行性疾病中的細(xì)胞死亡機(jī)制研究2. Alzheimer's disease: amyloid toxicity and metabolism, neuronal polarity and biomarkers老年性癡呆癥中的淀粉樣蛋白毒性和代謝，神經(jīng)元極性和生物標(biāo)記物研究3. Cell-cell communication in physiological and stress conditions在正常和應(yīng)激條件下的細(xì)胞間交流研究
著作論文
1. Sun X, Wu Y, Gu M, Zhang Y , MiR-342-5p Decreases Ankyrin G Level in Alzheimer’s Disease Transgenic Mouse Models , Cell Reports , 2013 , in press2. Chen Q, Sun X, Zhou X-H, Liu J-H, Wu J,Zhang Y, Wang J-H , N-terminal horseshoe conformation of DCC is functionally required for axon guidance and may be shared by other neural receptors , J CellSci , 2013 , 126: 186-1953. Sun X, Wang Y, Zhang J, Tu J, Wang X-J,Su X-D, Wang L, Zhang Y , Tunneling-nanotube direction determination in neuronsand astrocytes , Cell Death Dis , 2012 , 3: e438. DOI: 10.1038/cddis.2012.1774. Cui J, Wang Y, Dong Q, Wu S, Xiao X, HuJ, Chai Z and Zhang Y , Morphine protects against intracellular amyloid toxicity by inducing estradiol release and upregulation of Hsp70 , J Neurosci ,2011 , 31: 16277-162405. Wand Y, Cui J, Sun X and Zhang Y , Tunneling-nanotube development in astrocytes depends on p53 activation , Cell Death Differ , 2011, 18: 732-7426. Zhang Y, Xiong W, Lin X, Ma X and Yu L ,Roles of mu-opioid receptor phosphorylation in opioid tolerance and dependence, Neurosci Biobehav Rev , 2009 , 33: 1192-11977. Zhang Y and Yu L , Single-cell microinjection technology in cell biology , BioEssays , 2008 , 30: 606-610.8. Li M, Chen L, Lee D, Yu L and Zhang Y ,The Role of Intracellular Amyloid β in Alzheimer’s Disease , Prog Neurobiol , 2007, 17: 233-236.9. Zhang Y , Microinjection Technique and Protocol to Single Cells , Nat Protocols , 2007 , DOI: 10.1038/nprot.2007.48710. Zhang Y, Beitel L, Goodyer C, Trifiro Mand LeBlanc A , Estrogen and androgen protect against intracellular amyloidbeta toxicity , J Neurosci , 2004 , 24: 5315-5321.11. Zhang Y, McLauglin R, Vereker E,Goodyer C and LeBlanc A , Selectively cytotoxicty of intracellular amyloid betapeptide1-42 through p53 and Bax in cultured primary human neurons , J Cell Biol, 2002 , 156: 519-529.12. Zhang Y, Goodyer C and LeBlanc A ,Selective and protracted apoptosis in human primary neurons microinjected withactive caspase-3, -6, -7 and –8 , J Neurosci , 2000 , 20: 8384-8389.
榮譽(yù)記錄
2018年1月12日，由全國婦聯(lián)、中國科學(xué)技術(shù)協(xié)會(huì)、中國聯(lián)合國教科文組織全國委員會(huì)、歐萊雅中國共同舉辦的第十四屆“中國青年女科學(xué)家獎(jiǎng)”頒獎(jiǎng)典禮在京隆重舉行，張研獲得“中國青年女科學(xué)家”榮譽(yù)稱號。